What does the prefix derm- mean?
Derm- (also derma- and dermato-) comes from the Greek derma, which means "skin". It appears mostly in medical vocabulary, always related to the skin and its conditions.

Prefix · skin · tissue
Means "skin": dermatology, dermal, dermatitis, dermatologist, epidermis.
Written by Bryan López, English teacher · Updated
Derm- (also derma- and dermato-) comes from the Greek derma, which means "skin". It appears mostly in medical vocabulary, always related to the skin and its conditions.
The skin is the largest organ of the human body, which is why derm- shows up in everything that studies and treats it, from its layers to its most common problems. It also sneaks into zoology: there is a name for thick-skinned animals, like the elephant, that uses this same root. If you see derm- in a word, think skin.
Combines with Greek roots in medical and cosmetic vocabulary:
Pronunciation: /dɜːrm/.
derm-/dɜːrm/
Tap the button to hear how the prefix sounds. Each word in the table has its own audio.
"Epidermis" (epi- = upon/over + dermis): the protective outer surface of the skin. "Dermis" (derm- = skin): the thicker middle layer with structural and functional elements. The hypodermis (hypo- = below) is the deepest layer of subcutaneous fat. A mnemonic: EPI is on top, like an epicentre is above the centre.
A trick to remember it
Think of a dermatologist, the skin doctor: derm- = skin. dermatology, dermatitis.
Exercise 1 · Form the word
Exercise 2 · Pick the right one
What is the difference between "epidermis" and "dermis"?
The prefix derm- means "skin": dermatology, dermal, dermatitis, dermatologist, epidermis.
The prefix derm- is pronounced /dɜːrm/. For example, "dermatology".
"atology" becomes "dermatology". It is a typical example of the derm- prefix.
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