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Suffix · forms nouns

-gen / -genesis

From Greek "genein" (to produce, to originate): names what produces something or the origin of a process. Oxygen, pathogen.

In Spanish: -geno / -génesisScientific

Written by Bryan López, English teacher · Updated June 2026

What this suffix does

The suffix -gen comes from Greek "genein" (to beget, to produce) and names substances or agents that produce something, or indicates the origin of a process. From "oxy-" (acid/sharp) comes "oxygen"; from "hydro-" (water) comes "hydrogen". The extended form -genesis names the process of origin or creation: genesis, pathogenesis (origin of a disease). Spanish: oxygen → oxígeno, hydrogen → hidrógeno, pathogen → patógeno.

-gen: what produces

oxygen = what produces acids (original Greek theory) hydrogen = what produces water nitrogen = nitrogen pathogen = disease-producing agent allergen = allergy-producing agent carcinogen = cancer-producing substance mutagen = mutation-inducing agent halogen = salt-forming element (Cl, F, Br, I) androgen = male-producing hormone estrogen = female hormone (estro + gen)

-genesis: the process of origin

-genesis names the process of formation or creation: genesis = origin, beginning pathogenesis = how a disease originates biogenesis = origin of life from living matter abiogenesis = life from non-living matter embryogenesis = development of an embryo phylogenesis = evolutionary origin of a species Word family: -gen (agent), -genesis (process), -genic (adjective: carcinogenic), -geny (science of origin: phylogeny).

How it is formed

Root (what is produced or where it comes from) + gen (agent) or genesis (process).

  • element + gen (produces or is produced by)oxy = oxygen · hydro = hydrogen · nitro = nitrogen
  • causative agent + genpatho = pathogen · aller = allergen · carcino = carcinogen · muta = mutagen · andro = androgen
  • root + genesis (process of origin)bio = biogenesis · patho = pathogenesis · phylo = phylogenesis · embryo = embryogenesis

Family: -gen (agent), -genesis (process), -genic (adjective: produces or is caused by). carcinogen → carcinogenic. pathogen → pathogenic. Also: -geny (science): phylogeny.

How it is pronounced

-gen / -genesis/dʒɛn/ or /dʒɛnɪsɪs/ · 'jen' or 'JEN-ih-sis'

Tap the button to hear how the ending sounds. Each word in the table has its own audio.

Examples

Base word
With -gen / -genesis
In a phrase
  • oxy (acid)oxygenThe brain can survive only a few minutes without oxygen.
  • hydro (water)hydrogenMany buses in the city are now powered by hydrogen fuel cells.
  • nitronitrogenAbout 78 percent of the air we breathe is made up of nitrogen.
  • patho (disease)pathogenWearing a mask helps stop an airborne pathogen from spreading to others.
  • aller (reaction)allergenPollen is the most common allergen for people who suffer from hay fever.
  • carcino (cancer)carcinogenCigarette smoke contains more than one known carcinogen that damages the lungs.
  • muta (change)mutagenUV radiation acts as a mutagen by altering the DNA inside skin cells.
  • halo (salt)halogenWe replaced the old halogen lamp with a more energy-efficient LED bulb.
  • andro (male)androgenA doctor may check androgen levels when a patient shows certain hormonal symptoms.
  • bio (life)biogenesisThe theory of biogenesis states that all living things come from existing life.

Common mistakes

confusing "gene" (gene) and "-gen" (that produces)
"gene" = DNA unit; "-gen" suffix = agent that produces

"Gene" = a unit of heredity in DNA. "-gen" as suffix = an agent that produces something (pathogen, allergen). Different words with related origins but different functions.

oxigen / hidrogen
oxygen / hydrogen

In English: oxygen (not "oxigen"), hydrogen (not "hidrogen"). The -y- is part of the Greek root.

pathogen = pathology
pathogen = disease-causing agent

"Pathogen" = patógeno (bacterium, virus, fungus that causes disease). "Pathology" = the study of disease. Different words.

A trick to remember it

-gen = what produces or causes something. Key examples: oxygen, hydrogen, pathogen (disease-causing), allergen, carcinogen. Adjective: -genic (carcinogenic, pathogenic). Process: -genesis (biogenesis, pathogenesis).

Practise what you learned

Exercise 1 · Form the word

An agent that causes disease: patho___

Hint: patho + gen = ?

Exercise 2 · Pick the right one

"Carcinogen" means...

Exercise 3 · Pick the right one

What is the adjective form of "carcinogen"?

Frequently asked questions

What does the suffix -gen / -genesis mean in English?

The suffix -gen / -genesis from Greek "genein" (to produce, to originate): names what produces something or the origin of a process. Oxygen, pathogen. In Spanish it usually maps to -geno / -génesis.

How do you pronounce -gen / -genesis?

The ending -gen / -genesis is pronounced /dʒɛn/ or /dʒɛnɪsɪs/ · 'jen' or 'JEN-ih-sis'. For example, "oxygen".

Can you give an example of a word with -gen / -genesis?

"oxy (acid)" becomes "oxygen". It is a typical example of the -gen / -genesis suffix.

Other useful suffixes

  • -itis

    Indicates inflammation of an organ or body part: arthr + itis = arthritis.

  • -lysis

    From Greek "lysis" (loosening, dissolving): indicates decomposition, separation or dissolution. Analysis, dialysis.

  • -ology / -logy

    Names a science or field of study: bio + ology = biology.

Learn every English suffix

-tion, -ness, -ful, -ly, -able... every ending you need to understand thousands of words at once.

View all suffixes
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