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Suffix · forms nouns

-lysis

From Greek "lysis" (loosening, dissolving): indicates decomposition, separation or dissolution. Analysis, dialysis.

In Spanish: -lisisScientific

Written by Bryan López, English teacher · Updated June 2026

What this suffix does

The suffix -lysis comes from Greek "lysis" (to loosen, to dissolve) and indicates a process of decomposition, separation or dissolution of a substance or structure. From "ana-" (up, through) comes "analysis" (separating into parts to examine); from "dia-" (through) comes "dialysis" (filtering blood through a membrane). Spanish: analysis → análisis, dialysis → diálisis, paralysis → parálisis, hydrolysis → hidrólisis.

The most important -lysis words

analysis = separating something into its parts to examine them paralysis = loss of muscle function (nerves "dissolved") dialysis = blood filtration through a membrane hydrolysis = chemical breakdown by water electrolysis = decomposition by electric current photolysis = decomposition by light catalysis = acceleration of a reaction by a catalyst psychoanalysis = Freudian analytical method hemolysis = rupture of red blood cells fibrinolysis = dissolving of blood clots

The word family: -lysis, -lyze/-lyse, -lytic

-lysis is the noun; its full family: -lyze (US) / -lyse (UK) = the verb: to analyze/analyse, to paralyze/paralyse, to dialyze/dialyse. -lytic = adjective: analytic/analytical, catalytic, paralytic. Full example: hydrolysis → to hydrolyze/hydrolyse → hydrolytic. Practical example: catalytic converter (car exhaust cleaner) uses catalysis.

How it is formed

Greek/Latin root (what is dissolved or how) + lysis.

  • process prefix + lysisana (apart) = analysis · dia (through) = dialysis · kata (down) = catalysis · para = paralysis
  • dissolving agent + lysishydro (water) = hydrolysis · electro = electrolysis · photo (light) = photolysis · thermo (heat) = thermolysis
  • object that is dissolved + lysishemo (blood) = hemolysis · bacterio = bacteriolysis · fibrin = fibrinolysis

Family: -lysis (noun), -lyze/-lyse (verb), -lytic (adjective). analysis → analyze/analyse → analytical. catalysis → catalyze/catalyse → catalytic converter.

How it is pronounced

-lysis/lɪsɪs/ · sounds like 'LIH-sis'

Tap the button to hear how the ending sounds. Each word in the table has its own audio.

Examples

Base word
With -lysis
In a phrase
  • ana (apart)analysisThe team presented a detailed analysis of the sales figures last quarter.
  • paraparalysisAfter the accident, doctors warned him about the risk of permanent paralysis.
  • dia (through)dialysisShe goes to the clinic three times a week for her dialysis treatment.
  • hydro (water)hydrolysisHydrolysis breaks starch down into simpler sugars that the body can absorb.
  • electroelectrolysisMany people choose electrolysis as a permanent solution for unwanted facial hair.
  • kata (down)catalysisWithout catalysis, many chemical reactions in the body would be far too slow.
  • psycho + anapsychoanalysisHer therapist suggested psychoanalysis to explore the roots of her recurring anxiety.
  • hemo (blood)hemolysisThe lab technician noticed hemolysis in the blood sample and requested a new one.
  • photo (light)photolysisPhotolysis of water molecules is a key step in how plants produce oxygen.
  • fibrinfibrinolysisThe body relies on fibrinolysis to dissolve blood clots after an injury heals.

Common mistakes

analysys / analisys
analysis

analysis (not "analysys" or "analisys"). Plural: analyses /ˈænəlɪsiːz/.

paralyses as singular
paralysis (singular) / paralyses (plural)

"paralysis" is the singular noun; "paralyses" /pəˈræləsiːz/ is the plural noun. Do not confuse with the verb "paralyses" (3rd person: "the disease paralyses him").

dialisis / dialisis
dialysis

In English: "dialysis" (no accent). Pronunciation: daɪˈæl.ɪ.sɪs = die-AL-ih-sis.

A trick to remember it

-lysis = decomposition, separation or dissolution of something. Most common: analysis, paralysis, dialysis. Verb: -lyze/-lyse (analyze/analyse). Adjective: -lytic (analytic, catalytic). Practical everyday example: catalytic converter in cars.

Practise what you learned

Exercise 1 · Form the word

"Hydro___" = chemical breakdown by water:

Hint: hydro + lysis = ?

Exercise 2 · Pick the right one

What is the American English verb form of "analysis"?

Exercise 3 · Pick the right one

"Dialysis" is used to...

Frequently asked questions

What does the suffix -lysis mean in English?

The suffix -lysis from Greek "lysis" (loosening, dissolving): indicates decomposition, separation or dissolution. Analysis, dialysis. In Spanish it usually maps to -lisis.

How do you pronounce -lysis?

The ending -lysis is pronounced /lɪsɪs/ · sounds like 'LIH-sis'. For example, "analysis".

Can you give an example of a word with -lysis?

"ana (apart)" becomes "analysis". It is a typical example of the -lysis suffix.

Other useful suffixes

  • -gen / -genesis

    From Greek "genein" (to produce, to originate): names what produces something or the origin of a process. Oxygen, pathogen.

  • -itis

    Indicates inflammation of an organ or body part: arthr + itis = arthritis.

  • -ology / -logy

    Names a science or field of study: bio + ology = biology.

Learn every English suffix

-tion, -ness, -ful, -ly, -able... every ending you need to understand thousands of words at once.

View all suffixes
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