What does the prefix xeno- mean?
Xeno- comes from the Greek xenos, which means "foreign", "strange" or "unknown". It appears in scientific and social vocabulary.

Prefix · origin · foreign
Means "foreign" or "strange": xenophobia, xenon, xenophile, xenograft, xenobiotic.
Written by Bryan López, English teacher · Updated
Xeno- comes from the Greek xenos, which means "foreign", "strange" or "unknown". It appears in scientific and social vocabulary.
Xeno- appears in two worlds. In the social sciences, it talks about what we feel toward what comes from outside, whether fear or fondness. In science, it names things that are foreign to where they are: a gas that was named that way because it was hard to identify when it was discovered, a transplant between different species or a rock embedded inside another.
Combines with Greek roots in scientific and social vocabulary:
Pronunciation: /ˈzen.oʊ/ — the x is /z/ at the start of a word in English, not /ks/.
xeno-/ˈzen.oʊ/
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Unlike "extra" or "example" where x is /ks/ or /ɡz/, the x in xeno- is /z/ at the start of a word. "Xenon" = /ˈziː.nɒn/, "xenophobia" = /ˌzen.əˈfoʊ.bi.ə/. Predictable pattern: Greek-origin words starting with xen- always use /z/ in English.
A trick to remember it
Think of xenophobia, the fear of foreigners: xeno- = foreign, strange. xenophobia, xenophile.
Exercise 1 · Form the word
Exercise 2 · Pick the right one
Why is the noble gas called "xenon"?
The prefix xeno- means "foreign" or "strange": xenophobia, xenon, xenophile, xenograft, xenobiotic.
The prefix xeno- is pronounced /ˈzen.oʊ/. For example, "xenophobia".
"phobia" becomes "xenophobia". It is a typical example of the xeno- prefix.
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